The responsibility for determining what to disclose and what to withhold is on the individual prosecutor, and "the prudent prosecutor will resolve doubtful cases in favor of disclosure." (U.S. v. Agurs) To meet the due process duty, the prosecutor must have knowledge of evidence, and the evidence must still be in existence.
The decision by police officers to include particular information in a report or to make sure that physical evidence is preserved depends on their recognizing the potentially exculpatory nature of the evidence, and having some way to preserve it. This will not always be easy, but like the prosecutor, the prudent officer will resolve doubtful cases in favor of inclusion and retention, whenever possible.
The Supreme Court first considered an issue of failure to preserve in Killian v. U.S. FBI agents had made rough notes of their interviews with an undercover operative, and after incorporating the contents of the notes into finished reports, they destroyed the notes, as was their standard practice. The defendant argued that police failure to preserve the notes deprived him of due process.
The Supreme Court rejected this argument, ruling that since the contents of the notes were reflected in the official reports to which the defense had access, there was no prejudice to the defense. "If the notes were destroyed by the agents in good faith and in accord with their normal practice, their destruction did not constitute an impermissible destruction of evidence nor deprive defendant of any right."
The court next addressed a preservation issue in California v. Trombetta, in which the DUI defendant argued that police should have preserved an ampoule of his breath for independent analysis of blood-alcohol content. Although the California courts agreed with this assertion, the U.S. Supreme Court reversed and held that due process was not violated.