Once you start knocking on the doors of everyone he's ever been associated with, your suspect will quickly figure out he's a wanted man. This can be good in a lot of ways. First, he may be familiar with the system and just walk into the police department to give you a statement. Many times, this will happen if it's a smaller crime or a crime for which he wants to give his side of the story. This works especially well in domestic violence cases, where the suspect will want to exonerate himself by explaining he was actually the victim, regardless of what the evidence shows.
Checking with his buddies usually gets him bragging about what he did, too. This is great for the investigators, because when one of these friends gets caught in trouble of his own, he'll quickly spill the beans about what his buddy told him to try to get out of his own jam. This can help verify events and/or dates of the crime, and can also get you an updated location of where the suspect has been staying. It can also lead to the recovery of stolen property, as your suspect's buddy will usually be more than happy to tell you where the loot is stashed if he thinks he's getting a break.
If you find where your suspect is staying, you can use his paranoia to flush him out. Try calling the residence and ask for the suspect, or tell them the police are on the way. Pose as a housekeeper if he's in a hotel room, or another public service employee if he's in a house. Tell him you're towing his car or something similar to get him outside. This will usually get your suspect to either run out of the house to escape, or to come outside to investigate what's going on. Once he's in public, he's all yours.
Linking Suspects in Your Crime
Another great use of the power of association is linking multiple suspects to one crime. If you had a local business burglarized, and you have a suspect in mind, try running his name to see who his buddies are. Many times these will be more suspects in your crime, and their contact info gives you a great place to start your investigation. Sometimes the group has even been arrested for the same or similar crime in the past, making it a much stronger case.