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Six people were reported killed when a man drove a pickup truck down a lengthy stretch of a bike path next to the Hudson River in Lower Manhattan on Tuesday afternoon before he jumped out with what the NYPD called "two imitation firearms" and was shot by officers.

The attacker, in what was marked as a Home Depot truck, hit numerous people as he drove south on the bike path, officials said. At least 11 people were reported injured.

The driver was being treated at a nearby hospital. He also crashed into a school bus as he careened down as many as 20 city blocks near Stuyvesant High School, a senior law enforcement official said. It was unclear if anyone was on the bus.

A large section of the West Side Highway was closed for the investigation as hundreds of officers, including the bomb squad, responded to the scene. The truck came to a rest near Chambers and West Streets.

Police told the New York Times they are not looking for additional suspects.