A manhunt is underway in Chicago after two on-duty police officers were shot and wounded by an at-large gunman who fired "indiscriminately" in what is thought to be a targeted attack, the Chicago Police Department said.

The officers, both male, were conducting an investigation on the city's South Side when "one, possibly two vehicles, pulled alongside them and started firing indiscriminately at the officers," Chicago Police Superintendent Eddie Johnson said during a press conference early Wednesday morning.

One officer was shot in the arm and hip and the other in the back, Johnson said. Both are expected to make a complete recovery, he said. One officer was released from the hospital this morning, police said, reports ABC News.

"Right now, there's an extensive manhunt underway for the individuals responsible and we will get them," he added.

Police spokesman Anthony Guglielmi told The Associated Press, "We believe that the officers were definitely targeted."

The officers, who were dressed in plain clothes, but wore vests with police badges on them, were conducting a follow-up investigation to a previous incident when they were hit, according to authorities.

The police department is questioning three people of interest and two guns have been recovered, police said. It's believed the officers were shot by a high-powered weapon, according to police.